产品货号：
Z19405
中文名称：
JAK2抗体
英文名称：
Anti-JAK2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-JAK2 Antibody |
| 指标别名 | Janus kinase 2;JTK10;JAK2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | JAK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | JAK2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human JAK2.The immunogen is located within the last 50 amino acids of JAK2. |
| 计算分子量 | 131kDa |
| 成分 | JAK2 antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | JAK2 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | JAK2 is a member of the JAK family of kinases that also include JAK1,JAK3,and TYK2 (1,2).JAK kinases are activated following tyrosine phosphorylation of cytokine receptors after ligand binding.JAK2 activation promotes the recruitment and phosphorylation of STAT3 and STAT5.These transcription factors then translocate to the nucleus where they bind specific DNA promoter sequences resulting in the transcription of genes that regulate cell proliferation,differentiation,and apoptosis (3).Mice with a disrupted JAK2 gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis (4). |
| Uniprot ID | O60674 |
| 基因名全称 | Janus kinase 2 |
| 蛋白名全称 | Janus kinase 2 |
| 推荐稀释比 | JAK2 antibody can be used for detection of JAK2 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in mouse samples.All other applications and species not yet tested. |
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